These two sides know quite a lot about each other - with Tuesday's spectacular Championship victory for Southampton, coming from 3-0 down to win 4-3 at Leicester City, still fresh in the memory.
The Saints are going for a second treble over the Foxes, having also won both league games and an FA Cup tie in the 2007-2008 season.
- This will be the eighth FA Cup tie between Southampton and Leicester City and first since the pair met at the semi-final stage in April 2021, with the Foxes winning 1-0 at Wembley that day before going on to lift the trophy with a final win over Chelsea.
- Leicester City have faced Southampton twice before in the FA Cup fourth round, winning a reply 4-2 in January 1970 before losing 1-0 to the Saints at this stage in January 2006.
- After losing their last home FA Cup game against Burnley 2-1 in January last year, Southampton will be hoping to avoid losing consecutive FA Cup games on home soil for the first time since January 2016.
- Leicester have progressed from seven of their past nine FA Cup fourth-round ties since 2014-15 but did lose at this stage last season 2-1 against Manchester United. The Foxes were last eliminated at this stage in successive seasons in 2001-02 and 2002-03.
- Leicester's Stephy Mavididi has scored in all three of his FA Cup appearances for the club, getting a goal and an assist in their 2-0 third-round win against Cheltenham this season.
