Since last etching their name on a domestic trophy in 2018, Chelsea have won every European trophy on offer, as well as the Fifa Club World Cup last summer.
That last piece of domestic silverware was the FA Cup, which they won eight years ago under the guidance of Italian Antonio Conte.
After falling at the semi-final stage of the Carabao Cup this season to Arsenal, the FA Cup could present an opportunity for Liam Rosenior to land a first prize as Chelsea boss.
With the talent at his disposal and strength in depth - the Blues made seven changes from the side that drew with Leeds on Tuesday in the Premier League against Leeds - they will be among the favourites.
Talisman Cole Palmer was left at home, while Enzo Fernandez and Joao Pedro were among the substitutes.
Yet the Blues could still have been 3-0 up inside the opening 20 minutes with Estevao and Caicedo shining.
Once Neto struck a sumptuous opener, Hull City - who had won just one of their 35 previous games against Chelsea in all competitions - came under constant pressure.
Liam Delap, who was on loan at Hull in the 2023-24 campaign, impressively put his earlier misjudgement behind him to tee up his team-mates for further strikes.
With the Premier League title beyond them and out of the Carabao Cup, the FA Cup offers Chelsea a perfect route to Wembley and end their wait for domestic silverware.