Key players including Kai Havertz, William Saliba and Martin Ødegaard are carrying knocks, while Mikel Merino continues foot surgery recovery. Expect fringe players and academy graduates to feature as Arteta balances his Premier League title push with cup ambitions.
The Gunners have dominated previous encounters, winning sixteen of nineteen meetings, with their last competitive clash coming in the 2014 FA Cup semi-final.