Spurs are set to deploy a 4-1-2-3 formation with Pape Matar Sarr on the wing and Palhinha at centre-back. Randal Kolo Muani replaces Dominic Solanke, who is absent due to a throat issue, in the starting lineup.
Kolo Muani, who scored three goals in 27 appearances this season, all in Europe, joins Simons as the starting attackers.